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A further aspect of the invention encompasses a kit for amplifying a population of target nucleic acids. The log base 2 ratios of amplified cDNAs targets were plotted against the log base 2 ratio for unamplified cDNA target. The adaptor may comprise a universal priming sequence, as described above, or a homopolymeric sequence, such as poly-G or poly-C. WTAs were performed similar to those described above. The remaining 16 primers i. In another embodiment, the plurality of oligonucleotides may comprise the formula X p Z q , wherein X and Z are nucleotides as defined above, p and q range from 1 to 12, and the sum total of p and q is In yet another embodiment, the plurality of oligonucleotides may comprise the formula X p Z q , wherein X and Z are nucleotides as defined above, p and q range from 1 to 11, and the sum total of p and q is The method of claim 6, further comprising amplifying the library of replicated strands using a polymerase chain reaction. To facilitate understanding of the invention, a number of terms are defined below.

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